Nucleic Acid Vaccinations

7-slider_vaccinazioni_terapie_geniche_igea_medical

NUCLEIC ACID VACCINATION

INOCULATION OF NUCLEIC ACIDS INTO TISSUES TO OBTAIN THE IMMUNE RESPONSE

Nucleic acid vaccination involves inoculation into tissues (mainly muscle or dermis) of nucleic acids (DNA plasmids or RNA sequences) that encode the antigen(s) against which an immune response is sought.

This method exploits the endogenous production of the target antigen for prophylactic or therapeutic purposes.

IGEA technology significantly amplifies the transfer efficiency of genetic material by electroporation.

INOCULATION OF NUCLEIC ACIDS INTO TISSUES TO OBTAIN THE IMMUNE RESPONSE

This method exploits the endogenous production of the target antigen for prophylactic or therapeutic purposes.

IGEA technology significantly amplifies the transfer efficiency of genetic material by electroporation.

HOW DOES IT WORK?

Cliniporator^® FULL

Enables the injection of genetic material and the delivery of electrical pulses into both muscle and dermis.

E-gun Electrode

Injects the genetic material and delivers electrical pulse sequences in one simple procedure.

Electrical Pulses

Cause the formation of temporary pores in cell membranes, allowing nucleic acid to enter the cell.

Cell

Begins producing the protein encoded by the genetic material introduced within a few days of injection.

Cliniporator^® FULL

Enables the injection of genetic material and the delivery of electrical pulses into both muscle and dermis.

E-gun Electrode

Injects the genetic material and delivers electrical pulse sequences in one simple procedure.

Electrical Pulses

Cause the formation of temporary pores in cell membranes, allowing nucleic acid to enter the cell.

Cell

Begins producing the protein encoded by the genetic material introduced within a few days of injection.

BENEFITS

Nucleic acid vaccination offers a number of advantages over traditional vaccines

Efficiency

Activation of the humoral and cell-mediated immune response.
Local inflammation induced by electrical impulses provides an adjuvant effect.

Safety

Nucleic acid vaccination, unlike traditional vaccines that use live attenuated or inactivated pathogens, does not use any infectious agents, thus avoiding the risk of a potential return to virulence.

Speed of
Development

In a few months from the laboratory to the clinic.

Simplicity of the
Production Process

Fast production and formulation.
Highly reproducible large-scale production and purification processes.

Storage and
Shipping Stability

Thermostable.
It does not require the cold chain.

Efficiency

Activation of the humoral and cell-mediated immune response.
Local inflammation induced by electrical impulses provides an adjuvant effect.

Efficiency

Activation of the humoral and cell-mediated immune response.
Local inflammation induced by electrical impulses provides an adjuvant effect.

Safety

Nucleic acid vaccination, unlike traditional vaccines that use live attenuated or inactivated pathogens, does not use any infectious agents, thus avoiding the risk of a potential return to virulence.

Safety

Nucleic acid vaccination, unlike traditional vaccines that use live attenuated or inactivated pathogens, does not use any infectious agents, thus avoiding the risk of a potential return to virulence.

Speed of Development

In a few months from the laboratory to the clinic.

Speed of Development

In a few months from the laboratory to the clinic.

Simplicity of the Production Process

Fast production and formulation.
Highly reproducible large-scale production and purification processes.

Simplicity of the
Production Process

Fast production and formulation.
Highly reproducible large-scale production and purification processes.

Storage and Shipping Stability

Thermostable.
It does not require the cold chain.

Storage and
Shipping Stability

Thermostable.
It does not require the cold chain.

Find out more about the applications of nucleic acid vaccination:

INFECTIOUS DISEASES

TUMOURS